CSS / EPGA Vasculitis

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Eosinophilic Granulomatosis with Polyangiitis (EPGA)

Eosinophilic Granulomatosis with Polyangiitis  (EGPA) used to be known as Churg–Strauss syndrome (CSS) .  It is a rare autoimmune condition  that causes inflammation of the small and medium sized blood vessels.  It usually manifests itself in 3 stages. 

1990 Criteria for the Classification of Churg-Strauss Syndrome .  You need at least 4 out of the 6 criteria or a diagnosis of CSS / EPGA to be considered.

  • Asthma
  • Eosinophilia >10%
  • Neuropathy, mono or poly
  • Pulmonary infiltrates, non-fixed
  • Paranasal sinus abnormality
  • Extravascular eosinophils
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Pathway to better understanding CSS / EPGA, Vasculitis, Autoimmunity and Chronic Illness


Here is a list of sites if you are looking for more information on CSS / EPGA






title_vasculitisorgEUVAS — European Vasculitis Society



Cleveland Clinic

John Hopkins Vasculitis Clinic

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Merck Manuals


VPAN_bigThe Vasculitis Patient Advocacy Network (VPAN) is dedicated to improving the quality of life for all people affected by vasculitis through providing assistance in locating quality physician care, patient empowerment via education, and patient advocacy.